Entity Detail โ Knowledge Graph Node
This page aggregates everything SciDEX knows about FIGN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | FIGN |
| Function | FIGN is a AAA+ ATPase with microtubule-severing activity. |
| Primary Expression | various brain regions: |
| Molecular Weight | 49 kDa |
| Amino Acids | 425 aa |
| UniProt ID | Q8N8Y0 |
| Ensembl ID | ENSG00000101940 |
| GeneCards | FIGN |
| Human Protein Atlas | FIGN |
| N-terminal domain | Involved in protein interactions |
| AAA+ ATPase domain | Mediates ATP-dependent microtubule severing |
| C-terminal domain | Regulatory functions |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
FIGN["FIGN"]
neurodegeneration["neurodegeneration"]
FIGN -->|"implicated_in"| neurodegeneration
style FIGN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||