FLNA

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolFLNA
Namefilamin A
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OP

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This is an externally resolved entity

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