gene

FRRS1

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about FRRS1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

FRRS1 (Ferric Chelate Reductase 1) - A critical iron metabolism gene implicated in neurodegenerative diseases including Alzheimer's, Parkinson's, and disorders of brain iron accumulation

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🧬 Gene Info

Gene Symbol	FRRS1
Full Name	Ferric Chelate Reductase 1
Chromosome	9q34.3
Protein Type	Ferric Reductase (FRO1-like)
Function	encodes a critical enzyme involved in iron metabolism, functioning as a ferric chelate reductase that catalyzes the reduction of Fe(III) to Fe(II).
Molecular Weight	79 kDa
Amino Acids	711 aa
GeneCards	FRRS1
Human Protein Atlas	FRRS1
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

FRRS1 — Ferric Chelate Reductase 1

gene · 2556 words

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Pathway Diagram

graph TD
    FRRS1["FRRS1"]
    neurodegeneration["neurodegeneration"]
    FRRS1 -->|"implicated_in"| neurodegeneration
    style FRRS1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning FRRS1 in their description or question text

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