Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FZD6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | FZD6 |
| Full Name | Frizzled Class Receptor 6 |
| Chromosome | 8q22.3 |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | the developing nervous system and select adult tissues |
| Pathways | Wnt signaling |
| UniProt ID | O00144 |
| NCBI Gene ID | 8323 |
| Ensembl ID | ENSG00000164930 |
| OMIM | 603409 |
| GeneCards | FZD6 |
| Human Protein Atlas | FZD6 |
| Neural tube | Neuroepithelium |
| Brain | Cortex, hippocampus |
| Associated Diseases | Neural Tube Defects, Spina Bifida, Alzheimer's Disease |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
FZD6["FZD6"]
neurodegeneration["neurodegeneration"]
FZD6 -->|"implicated_in"| neurodegeneration
style FZD6 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning FZD6 in their description or question text
No additional research found