protein

FZD6PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FZD6PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

FZD6 (Frizzled-6) is a seven-transmembrane receptor that belongs to the Frizzled family of Wnt receptors. It activates both canonical and non-canonical Wnt signaling pathways, particularly the planar cell polarity (PCP) pathway.

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🔬 Protein Info

Gene Symbol	FZD6PROTEIN
Aliases	FZ-6, Frizzled 6
Protein Family	Frizzled (FZD) receptor family
Protein Type	Receptor
Function	is a seven-transmembrane receptor that belongs to the Frizzled family of Wnt receptors.
Subcellular Localization	Plasma membrane, endosomes
Molecular Weight	~71 kDa
UniProt ID	O00144
GeneCards	FZD6PROTEIN
Human Protein Atlas	FZD6PROTEIN
Protein Name	Frizzled-6 Receptor (FZD6)
Gene	FZD6
PDB	7EVW, 6BD4
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

fzd6-protein

protein · 1047 words

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Pathway Diagram

graph TD
    FZD6PROTEIN["FZD6PROTEIN"]
    neurodegeneration["neurodegeneration"]
    FZD6PROTEIN -->|"implicated_in"| neurodegeneration
    style FZD6PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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No papers found