gene

GALNT2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GALNT2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

GALNT2 (Polypeptide N-acetylgalactosaminyltransferase 2) - Key enzyme in mucin-type O-glycosylation implicated in lipid metabolism, Alzheimer's disease, and neurodegenerative processes

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🧬 Gene Info

Gene Symbol	GALNT2
Full Name	Polypeptide N-acetylgalactosaminyltransferase 2
Chromosome	1q42.2
Protein Type	Glycosyltransferase
Function	encodes a member of the UDP-GalNAc polypeptide N-acetylgalactosaminyltransferase family, commonly known as the GalNAc-transferase family or GALNT family.
Primary Expression	most tissues with particularly high expression in the brain, liver, and adipose tissue
Molecular Weight	75 kDa
Amino Acids	662 aa
GeneCards	GALNT2
Human Protein Atlas	GALNT2
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GALNT2 — Polypeptide N-acetylgalactosaminyltransferase 2

gene · 2507 words

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Pathway Diagram

graph TD
    GALNT2["GALNT2"]
    neurodegeneration["neurodegeneration"]
    GALNT2 -->|"implicated_in"| neurodegeneration
    style GALNT2 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
    style neurodegeneration fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning GALNT2 in their description or question text

No additional research found