gene

GALR2

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about GALR2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for GALR2 Gene

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🧬 Gene Info

Gene Symbol	GALR2
Full Name	Galanin Receptor 2
Chromosome	17q25.3
Protein Type	Receptor
Function	is a G protein-coupled receptor that mediates the neuroprotective and modulatory effects of the neuropeptide galanin in the central and peripheral nervous systems.
Amino Acids	369 aa
Exons	4
Pathways	MAPK pathway, PI3K
Ensembl ID	ENSG00000141404
GeneCards	GALR2
Human Protein Atlas	GALR2
Glutamate-induced toxicity	GALR2 agonists reduce neuronal death
NMDA receptor modulation	Alters NMDA receptor function
Calcium homeostasis	Stabilizes intracellular calcium levels
Glutamate release	Modulated by GALR2
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GALR2 Gene

gene · 1271 words

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Pathway Diagram

graph TD
    GALR2["GALR2"]
    neurodegeneration["neurodegeneration"]
    GALR2 -->|"implicated_in"| neurodegeneration
    style GALR2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

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Experiments (0)

Experimental studies targeting or related to this entity

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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

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Related Research

Hypotheses and analyses mentioning GALR2 in their description or question text

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