gene

GDNFR

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about GDNFR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Gene page for GDNFR

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🧬 Gene Info

Gene Symbol	GDNFR
Full Name	GDNF Family Receptor Alpha 1
Chromosome	10q26.13
Protein Type	Receptor
Function	The GDNFR gene encodes GDNF Family Receptor Alpha 1, a cell surface receptor that binds GDNF and mediates its neurotrophic effects.
Primary Expression	Substantia nigra, Spinal cord, Motor neurons, Peripheral nervous system
Pathways	PI3K, MAPK
UniProt ID	Q9NZU5
NCBI Gene ID	3912
Ensembl ID	ENSG00000027697
OMIM	601836
GeneCards	GDNFR
Human Protein Atlas	GDNFR
Databases	GeneCards HPA STRING

🔮 Predicted Structure: GDNFR — AlphaFold Q9NZU5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GDNFR — GDNF Family Receptor Alpha 1

gene · 597 words

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Pathway Diagram

graph TD
    GDNFR["GDNFR"]
    neurodegeneration["neurodegeneration"]
    GDNFR -->|"implicated_in"| neurodegeneration
    style GDNFR fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning GDNFR in their description or question text

No additional research found