GEMIN4

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolGEMIN4
Namegem nuclear organelle associated protein 4
Typeprotein-coding
Sourcemygene

Summary

The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not

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