Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GEMIN5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | GEMIN5 |
| Chromosome | 14q12 |
| Function | is a critical component of the SMN complex, the master regulator of spliceosomal snRNP (small nuclear ribonucleoprotein) assembly. |
| Molecular Weight | 175 kDa |
| Amino Acids | 1588 aa |
| Ensembl ID | ENSG00000140988 |
| GeneCards | GEMIN5 |
| Human Protein Atlas | GEMIN5 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
GEMIN5["GEMIN5"]
neurodegeneration["neurodegeneration"]
GEMIN5 -->|"implicated_in"| neurodegeneration
style GEMIN5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||