gene

GEMIN8

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GEMIN8: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections

0Hypotheses

0Analyses

1Outgoing

1Incoming

0Experiments

0Debates

Summary

GEMIN8 (Gem-Associated Protein 8) - a core component of the SMN complex essential for snRNP assembly and spliceosomal function, implicated in spinal muscular atrophy

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🧬 Gene Info

Gene Symbol	GEMIN8
Full Name	Gem-Associated Protein 8
Chromosome	Xp21.3
Function	snRNA binding to SMN complex via Gemin5
Molecular Weight	37 kDa
Amino Acids	346 aa
Exons	2
UniProt ID	Q9BYX4
NCBI Gene ID	54935
Ensembl ID	ENSG00000165275
OMIM	609653
GeneCards	GEMIN8
Human Protein Atlas	GEMIN8
Associated Diseases	neurodegeneration
KG Connections	2 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: GEMIN8 — AlphaFold Q9BYX4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GEMIN8 Gene

gene · 2761 words

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Pathway Diagram

graph TD
    GEMIN8["GEMIN8"]
    neurodegeneration["neurodegeneration"]
    GEMIN8 -->|"implicated_in"| neurodegeneration
    style GEMIN8 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (1)

Target	Relation	Type	Str
ds-83b31ef18d49	provides_data_for	dataset	1.00

Incoming (1)

Source	Relation	Type	Str
ds-83b31ef18d49	data_in	dataset	1.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GEMIN8 in their description or question text

No additional research found