GFAP

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolGFAP
Nameglial fibrillary acidic protein
Typeprotein-coding
Sourcemygene

Summary

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].

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