Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GIGYF1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | GIGYF1 |
| Protein Type | Receptor |
| Function | GIGYF1 participates in signaling pathways |
| Subcellular Localization | ### Signaling Pathway Interactions |
| Molecular Weight | 200 kDa |
| Amino Acids | 819 aa |
| Exons | Multiple coding exons |
| Pathways | PI3K, MAPK pathway, mTOR, MAPK, signaling: ### Signaling Pathways |
| Ensembl ID | ENSG00000146830 |
| GeneCards | GIGYF1 |
| Human Protein Atlas | GIGYF1 |
| Alternative Splicing | Produces multiple transcript variants |
| Promoter | Contains regulatory elements |
| GYF Domain | Proline-rich binding motif that mediates protein-protein interactions |
| coiled-coil regions | Facilitate dimerization and complex formation |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
GIGYF1["GIGYF1"]
neurodegeneration["neurodegeneration"]
GIGYF1 -->|"implicated_in"| neurodegeneration
style GIGYF1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||