protein

GLE1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GLE1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

1Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

Page for GLE1 Protein

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🔬 Protein Info

Gene Symbol	GLE1
Full Name	GLE1 RNA Export Mediator
Chromosome	9q34.3
Function	GLE1 performs several critical cellular functions that are especially important in neurons:
Molecular Weight	100 kDa
UniProt ID	[Q9BSC7](https://www.uniprot.org/uniprot/Q9BSC7)
Ensembl ID	ENSG00000108654
OMIM	603371
GeneCards	GLE1
Human Protein Atlas	GLE1
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

GLE1 — GLE1 RNA Export Mediator

gene · 955 words

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Validated Hypothesis: GLE1-Mediated mRNA Export Defect Creates Translation-Competent mRNA Starvation in ALS Motor Neuron Axons

hypothesis · 1162 words

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GLE1 Protein

protein · 959 words

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GLE1 Protein

redirect · 701 words

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Pathway Diagram

graph TD
    GLE1["GLE1"]
    neurodegeneration["neurodegeneration"]
    GLE1 -->|"implicated_in"| neurodegeneration
    style GLE1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
GLE1-Mediated mRNA Export Defect Creates Translation-Compete	0.823	als	-

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GLE1 in their description or question text

No additional research found