gene

GLRA3

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about GLRA3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

GLRA3

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🧬 Gene Info

Gene Symbol	GLRA3
Full Name	Glycine Receptor Alpha 3
Chromosome	4q34.3
Protein Type	Receptor
Function	May play role in visual processing and light adaptation
Primary Expression	retinal neurons - Signal processing: Contributes to glycinergic inhibition in visual pathways - Function: May play role in visual processing a
UniProt ID	P47869
NCBI Gene ID	8001
Ensembl ID	ENSG00000132518
GeneCards	GLRA3
Human Protein Atlas	GLRA3
Subunit composition	Can form homomeric or heteromeric channels with other alpha subunits
Pharmacological profile	Distinct agonist/antagonist sensitivity from alpha-1/2
Developmental expression	Present throughout development
Regional distribution	Highest in spinal cord dorsal horn and retina
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: GLRA3 — AlphaFold P47869 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GLRA3

gene · 524 words

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Pathway Diagram

graph TD
    GLRA3["GLRA3"]
    neurodegeneration["neurodegeneration"]
    GLRA3 -->|"implicated_in"| neurodegeneration
    style GLRA3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning GLRA3 in their description or question text

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