gene

GLRB

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about GLRB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Glycine receptor beta subunit

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🧬 Gene Info

Gene Symbol	GLRB
Chromosome	4q34.3
Protein Type	Gene
Function	The GLRB gene encodes the Glycine Receptor Beta, a ligand-gated chloride channel receptor that mediates fast inhibitory neurotransmission in the spinal cord and brainstem.
Primary Expression	the spinal cord, brainstem, and retina
Molecular Weight	55 kDa
Amino Acids	210 aa
GeneCards	GLRB
Human Protein Atlas	GLRB
Gene	GLRB (chromosome 4q34.3)
Protein Class	Glycine receptor subunit (Cys-loop receptor family)
Primary Localization	Postsynaptic membranes, synapses
Disease Associations	Hyperekplexia, neurological disorders
Therapeutic Relevance	Target for synaptic modulators
Associated Diseases	Hyperekplexia, neurological disorders
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

GLRB Gene

gene · 981 words

→

GLRB Protein

protein · 874 words

→

Pathway Diagram

graph TD
    GLRB["GLRB"]
    neurodegeneration["neurodegeneration"]
    GLRB -->|"implicated_in"| neurodegeneration
    style GLRB fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning GLRB in their description or question text

No additional research found