Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GLUR5PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | GLUR5PROTEIN |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| GeneCards | GLUR5PROTEIN |
| Human Protein Atlas | GLUR5PROTEIN |
| N-terminal domain (ATD) | Lobed extracellular domain involved in subunit assembly |
| Ligand-binding domain (S1/S2) | Binds glutamate and kainate |
| Transmembrane domains (M1-M4) | Form the ion channel pore |
| C-terminal domain (CTD) | Intracellular tail for trafficking and interactions |
| GluR5a | Standard isoform |
| GluR5b | Alternative splice variant with different C-terminus |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
GLUR5PROTEIN["GLUR5PROTEIN"]
neurodegeneration["neurodegeneration"]
GLUR5PROTEIN -->|"implicated_in"| neurodegeneration
style GLUR5PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning GLUR5PROTEIN in their description or question text
No additional research found