Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GNG4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | GNG4 |
| Full Name | G Protein Subunit Gamma 4 |
| Chromosome | 14q21.3 |
| Primary Expression | photoreceptor cells and is essential for phototransduction [@retinal_phototransduction_2002] |
| Molecular Weight | 10 kDa |
| Pathways | MAPK, MAPK Pathway |
| UniProt ID | [P50150](https://www.uniprot.org/uniprot/P50150) |
| Ensembl ID | ENSG00000150316 |
| OMIM | 604773 |
| GeneCards | GNG4 |
| Human Protein Atlas | GNG4 |
| Retina | Photoreceptor cells, bipolar cells, and ganglion cells |
| Hippocampus | Pyramidal neurons in CA regions |
| Cerebral cortex | Layer-specific cortical neurons |
| Cerebellum | Purkinje cells and granule cells |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
GNG4["GNG4"]
neurodegeneration["neurodegeneration"]
GNG4 -->|"implicated_in"| neurodegeneration
style GNG4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning GNG4 in their description or question text
No additional research found