gene

GNS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GNS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	GNS
Full Name	N-Acetylglucosamine-6-Sulfatase
Aliases	Page for GNS Protein
Chromosome	12q14.3
Protein Type	Enzyme
Function	encodes a lysosomal enzyme that catalyzes the hydrolysis of sulfate groups from the N-acetylglucosamine-6-sulfate residues of heparan sulfate and related glycosaminoglycans (GAGs).
Molecular Weight	56 kDa
Amino Acids	535 aa
Exons	14
UniProt ID	P15546
NCBI Gene ID	2799
Ensembl ID	ENSG00000135638
OMIM	612340
GeneCards	GNS
Human Protein Atlas	GNS
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: GNS — AlphaFold P15546 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

GNS — N-Acetylglucosamine-6-Sulfatase

gene · 2242 words

→

GNS Protein - N-Acetylglucosamine-6-Sulfatase

protein · 581 words

→

Pathway Diagram

graph TD
    GNS["GNS"]
    neurodegeneration["neurodegeneration"]
    GNS -->|"implicated_in"| neurodegeneration
    style GNS fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GNS in their description or question text

No additional research found