GPX1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolGPX1
Nameglutathione peroxidase 1
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance; therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulati

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