GPX4

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolGPX4
Nameglutathione peroxidase 4
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death. It is als

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