Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GRAMD1A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | GRAMD1A |
| Full Name | GRAMD1A (GRAM Domain Containing 1A) |
| Aliases | GRAM Domain Containing 1A |
| Chromosome | 19q13.43 |
| Protein Type | Gene |
| Function | GRAMD1A functions as a lipid-binding protein with several key roles |
| Primary Expression | brain tissue and has several connections to nervous system function: [@lipid2018] |
| Subcellular Localization | Endoplasmic reticulum membrane, lipid droplets |
| Molecular Weight | ~59 kDa |
| Amino Acids | 526 aa |
| UniProt ID | Q9BY67 |
| NCBI Gene ID | 8395 |
| Ensembl ID | ENSG00000033122 |
| GeneCards | GRAMD1A |
| Human Protein Atlas | GRAMD1A |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
GRAMD1A["GRAMD1A"]
neurodegeneration["neurodegeneration"]
GRAMD1A -->|"implicated_in"| neurodegeneration
style GRAMD1A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning GRAMD1A in their description or question text
No additional research found