GRID2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolGRID2
Nameglutamate ionotropic receptor delta type subunit 2
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar P

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