gene

GRIK5

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about GRIK5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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Summary

Page for GRIK5 - Glutamate Receptor Kainate Type Subunit 5

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🧬 Gene Info

Gene Symbol	GRIK5
Full Name	Glutamate Receptor Kainate Type Subunit 5
Aliases	Page for GRIK5, Page for GRIK5 Protein
Chromosome	19q13.33
Protein Type	Receptor
Function	encodes the glutamate receptor 5 (GluR5) subunit, also known as kainate receptor subunit 5 (KA5)
Primary Expression	hypothalamic nuclei and regulates hormone release
Molecular Weight	106 kDa
UniProt ID	Q9NSU7
NCBI Gene ID	2896
Ensembl ID	ENSG00000146013
OMIM	604765
GeneCards	GRIK5
Human Protein Atlas	GRIK5
Ligand-binding domain (LBD)	The extracellular domain contains the glutamate binding site, which undergoes conformational changes upon agonist binding
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: GRIK5 — AlphaFold Q9NSU7 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

GRIK5 - Glutamate Receptor Kainate Type Subunit 5

gene · 924 words

→

GRIK5 Protein - Glutamate Receptor Kainate Type Subunit

protein · 709 words

→

Pathway Diagram

graph TD
    GRIK5["GRIK5"]
    neurodegeneration["neurodegeneration"]
    GRIK5 -->|"implicated_in"| neurodegeneration
    style GRIK5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GRIK5 in their description or question text

No additional research found