Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GRM6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | GRM6 |
| Function | The GRM6 gene encodes mGluR6 (Glutamate Metabotropic Receptor 6), a member of the metabotropic glutamate receptor family. |
| Primary Expression | retinal ON-bipolar cells where it mediates synaptic transmission in the visual pathway |
| Ensembl ID | ENSG00000113282 |
| GeneCards | GRM6 |
| Human Protein Atlas | GRM6 |
| Associated Diseases | Congenital Stationary Night Blindness, High Myopia |
| KG Connections | 3 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
GRM6["GRM6"]
mGluR6(["mGluR6"])
Congenital_Stationary_Night_Blindness["Congenital Stationary Night Blindness"]
High_Myopia["High Myopia"]
neurodegeneration["neurodegeneration"]
GRM6 -->|"associated with"| mGluR6
GRM6 -->|"causes"| Congenital_Stationary_Night_Blindness
GRM6 -->|"associated with"| High_Myopia
GRM6 -->|"implicated in"| neurodegeneration
style GRM6 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
style mGluR6 fill:#1a237e,stroke:#4fc3f7,stroke-width:2px,color:#fff
style Congenital_Stationary_Night_Blindness fill:#3e1a1a,stroke:#ef5350,stroke-width:2px,color:#fff
style High_Myopia fill:#3e1a1a,stroke:#ef5350,stroke-width:2px,color:#fff
style neurodegeneration fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| mGluR6 | associated_with | protein | 0.90 |
| Congenital Stationary Night Blindness | causes | disease | 0.90 |
| High Myopia | associated_with | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||