gene

GTF2H4

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about GTF2H4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	GTF2H4
Chromosome	6p21.33
Function	is a human gene located on chromosome 6p21.
Molecular Weight	46 kDa
Amino Acids	413 aa
Ensembl ID	ENSG00000168407
GeneCards	GTF2H4
Human Protein Atlas	GTF2H4
XPB (ERCC3)	3'-5' DNA helicase with ATPase activity
XPD (ERCC2)	5'-3' DNA helicase with ATPase activity
p62 (GTF2H1)	Scaffold subunit
p52 (GTF2H4)	Stabilizer and regulatory subunit
p44 (GTF2H2)	Ssl1 ortholog, E3 ubiquitin ligase
p34 (GTF2H3)	Assembly factor
cdk7	Kinase subunit
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GTF2H4 (General Transcription Factor IIH Subunit 4)

gene · 2548 words

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Pathway Diagram

graph TD
    GTF2H4["GTF2H4"]
    neurodegeneration["neurodegeneration"]
    GTF2H4 -->|"implicated_in"| neurodegeneration
    style GTF2H4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning GTF2H4 in their description or question text

No additional research found