HDAC1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolHDAC1
Namehistone deacetylase 1
Typeprotein-coding
Sourcemygene

Summary

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p

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