Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HDAC2/HDAC3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:HDAC2/HDAC3 | data_in | dataset_row | 0.00 |
| metabolic_neuroscience | associated_with | disease | 0.40 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:HDAC2/HDAC3 | data_in | dataset_row | 0.00 |
| Cp/Cebpα/Mir34A Pathway | mediates | pathway | 0.90 |
| h-d7212534 | targets | hypothesis | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Epigenetic Priming Ketone Protocol | 0.661 | metabolic-neuroscience | Gene Regulatory Network Inference in Alz |
Scientific analyses that reference this entity
metabolic neuroscience | 2026-04-03 | 7 hypotheses Top: 0.780
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| P-tau217 correlates with neurodegeneration in Alzheimer's disease, and targeting [PMID:38513667] | Zhang D, Zhang W, Ming C, Gao X, Yuan H, | Neuron | 2024 | 0 |
| Tau interactome maps synaptic and mitochondrial processes associated with neurod [PMID:35063084] | Tracy TE, Madero-Pérez J, Swaney DL, Cha | Cell | 2022 | 0 |
| Tau interactome maps synaptic and mitochondrial processes associated with neurod [PMID:35063084] | Tracy TE, Madero-Pérez J, Swaney DL, Cha | Cell | 2022 | 0 |
| A glycolytic shift in Schwann cells supports injured axons. [PMID:32807950] | ["Babetto Elisabetta", "Wong Keit Men", | Nature neuroscience | 2020 | 0 |
| Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-de [PMID:30643298] | Melamed Ze'ev; López-Erauskin Jone; | Nature neuroscience | 2019 | 0 |
| Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-de [PMID:30643298] | Melamed Z, López-Erauskin J, Baughn MW, | Nature neuroscience | 2019 | 0 |
| ER stress and the unfolded protein response in neurodegeneration. [PMID:28731040] | Hetz C, Saxena S | Nature reviews. Neurology | 2017 | 0 |
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning HDAC2/HDAC3 in their description or question text
No additional research found