gene

HDDX3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HDDX3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

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Summary

HEXML/DEAD-Box Helicase 3 Gene

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🧬 Gene Info

Gene Symbol	HDDX3
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	many cancers
Amino Acids	662 aa
Exons	16
GeneCards	HDDX3
Human Protein Atlas	HDDX3
Motif I (Walker A/AGXXXXGKST)	ATP binding
Motif II (DEAD)	ATP hydrolysis (helicase activity)
Motif III	ATP-dependent RNA unwinding
Motif IV	RNA binding
Motif V (Q motif)	RNA binding specificity
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

HEXML/DEAD-Box Helicase 3 Gene

gene · 780 words

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Pathway Diagram

graph TD
    HDDX3["HDDX3"]
    neurodegeneration["neurodegeneration"]
    HDDX3 -->|"implicated_in"| neurodegeneration
    style HDDX3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning HDDX3 in their description or question text

No additional research found