gene

HNRNAP2B1

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about HNRNAP2B1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

HNRNPA2B1 Gene

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🧬 Gene Info

Gene Symbol	HNRNPA2B1
Full Name	Heterogeneous Nuclear Ribonucleoprotein A2/B1
Chromosome	7p15.2
Function	HNRNPA2B1 contains two RNA recognition motifs (RRMs) and a glycine-rich low-complexity domain similar to HNRNPA1.
Primary Expression	both neuronal and non-neuronal tissues
Amino Acids	341 aa
UniProt ID	P22626
NCBI Gene ID	3181
Ensembl ID	ENSG00000122566
OMIM	600124
GeneCards	HNRNPA2B1
Human Protein Atlas	HNRNPA2B1
Alternative splicing regulation	HNRNPA2B1 regulates splicing of numerous pre-mRNAs, particularly those involved in neuronal development and synaptic function.
mRNA transport	The protein facilitates cytoplasmic transport of specific mRNAs.
Telomere maintenance	HNRNPA2B1 interacts with telomerase and contributes to telomere length regulation.
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: HNRNAP2B1 — AlphaFold P22626 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

HNRNPA2B1 Gene

gene · 650 words

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Pathway Diagram

graph TD
    HNRNAP2B1["HNRNAP2B1"]
    neurodegeneration["neurodegeneration"]
    HNRNAP2B1 -->|"implicated_in"| neurodegeneration
    style HNRNAP2B1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning HNRNAP2B1 in their description or question text

No additional research found