Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HNRNPG: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
HNRNPG encodes an RNA-binding protein with RRM domains, involved in alternative splicing, mRNA stability, and transport, implicated in ALS, FTD, and SMA
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| Gene Symbol | HNRNPG |
| Full Name | Heterogeneous Nuclear Ribonucleoprotein G |
| Chromosome | 2p22.2 |
| Protein Family | hnRNP G family |
| Function | encodes an RNA-binding protein that plays critical roles in post-transcriptional gene regulation. |
| Molecular Weight | 55 kDa |
| Amino Acids | 497 aa |
| UniProt ID | [Q9Y676](https://www.uniprot.org/uniprot/Q9Y676) |
| Ensembl ID | ENSG00000197746 |
| GeneCards | HNRNPG |
| Human Protein Atlas | HNRNPG |
| Multiple exons | Complex genomic organization |
| Alternative splicing | Generates multiple transcript variants |
| Promoter region | Contains regulatory elements for tissue-specific expression |
| HNRNPG (RBMX) | The canonical member |
| Associated Diseases | ALS |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
HNRNPG["HNRNPG"]
neurodegeneration["neurodegeneration"]
HNRNPG -->|"implicated_in"| neurodegeneration
style HNRNPG fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning HNRNPG in their description or question text
No additional research found