gene

HNRNRAB

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about HNRNRAB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

HNRNPAB Gene

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🧬 Gene Info

Gene Symbol	HNRNRAB
Chromosome	10q26.3
Function	encodes a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family of RNA-binding proteins.
Primary Expression	most other tissues at moderate levels
Molecular Weight	36 kDa
Amino Acids	305 aa
Exons	9
Ensembl ID	ENSG00000139718
GeneCards	HNRNRAB
Human Protein Atlas	HNRNRAB
Brain	High expression throughout the brain, with particular abundance in neurons.
Spinal Cord	Significant expression in motor neurons, the cell type affected in ALS.
Systemic Tissues	Expressed in most other tissues at moderate levels.
Cellular Localization	Predominantly nuclear, with some cytoplasmic localization.
Splice Site Selection	The protein influences the selection of alternative splice sites.
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

HNRNPAB Gene

gene · 1595 words

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Pathway Diagram

graph TD
    HNRNRAB["HNRNRAB"]
    neurodegeneration["neurodegeneration"]
    HNRNRAB -->|"implicated_in"| neurodegeneration
    style HNRNRAB fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning HNRNRAB in their description or question text

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