Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HSPA10: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | HSPA10 |
| Full Name | Heat Shock Protein Family A Member 10 |
| Chromosome | 12q13.12 |
| Protein Type | Chaperone |
| Function | Like other Hsp70 family members, HSPA10 utilizes ATP-dependent substrate binding and release cycles to facilitate protein homeostasis. |
| Primary Expression | Ubiquitous, highest in lymphoid tissues, testes, placenta |
| Subcellular Localization | the cytosol and nucleus. HSPA10 is constitutively expressed at low levels and is upregulated in response to various cell |
| Amino Acids | 641 aa |
| UniProt ID | P54652 |
| NCBI Gene ID | 3336 |
| Ensembl ID | ENSG00000113013 |
| OMIM | 610175 |
| GeneCards | HSPA10 |
| Human Protein Atlas | HSPA10 |
| T-cell activation | HSPA10 is overexpressed in activated T cells and functions as a co-stimulatory molecule |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
HSPA10["HSPA10"]
neurodegeneration["neurodegeneration"]
HSPA10 -->|"implicated_in"| neurodegeneration
style HSPA10 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning HSPA10 in their description or question text
No additional research found