gene

HSPB5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HSPB5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

0Debates

Summary

Page for HSPB5 — Heat Shock Protein Beta 5

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🧬 Gene Info

Gene Symbol	HSPB5
Full Name	Heat Shock Protein Family B (Small) Member 5 (Alpha B-Crystallin)
Aliases	Heat Shock Protein Beta 5
Chromosome	11q23.1
Protein Type	Chaperone
Function	HSPB5 (Heat Shock Protein Family B Member 5), also known as alpha B-crystallin (CRYAB), is a small heat shock protein with molecular chaperone activity
Amino Acids	175 aa
UniProt ID	P02511
NCBI Gene ID	9369
Ensembl ID	ENSG00000120063
OMIM	123610
GeneCards	HSPB5
Human Protein Atlas	HSPB5
Molecular chaperone	Prevents protein aggregation under stress
Cytoskeletal stabilizer	Protects intermediate filaments
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: HSPB5 — AlphaFold P02511 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

HSPB5 — Heat Shock Protein Beta 5

gene · 793 words

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HSPB5 Protein — Alpha B-Crystallin

protein · 1241 words

→

Pathway Diagram

graph TD
    HSPB5["HSPB5"]
    neurodegeneration["neurodegeneration"]
    HSPB5 -->|"implicated_in"| neurodegeneration
    style HSPB5 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
    style neurodegeneration fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning HSPB5 in their description or question text

No additional research found