gene

HTR1B

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about HTR1B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for htr1b Gene

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🧬 Gene Info

Gene Symbol	HTR1B
Full Name	5-Hydroxytryptamine Receptor 1B
Chromosome	6q14.2
Protein Family	5-HT1 receptor family (GPCR)
Protein Type	G protein-coupled receptor
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	the brain and plays key roles in mood regulation, aggression, impulsivity, and various neuropsychiatric disorders
Molecular Weight	50 kDa
Pathways	MAPK
UniProt ID	P28222
NCBI Gene ID	3351
Ensembl ID	ENSG00000149212
GeneCards	HTR1B
Human Protein Atlas	HTR1B
Adenylate Cyclase Inhibition	Reduces cAMP levels
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: HTR1B — AlphaFold P28222 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

htr1b Gene

gene · 593 words

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Pathway Diagram

graph TD
    HTR1B["HTR1B"]
    neurodegeneration["neurodegeneration"]
    HTR1B -->|"implicated_in"| neurodegeneration
    style HTR1B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning HTR1B in their description or question text

No additional research found