protein

HTR1FPROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HTR1FPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

The 5-HT1F receptor is a serotonin receptor subtype belonging to the G protein-coupled receptor (GPCR) superfamily. It is negatively coupled to adenylyl cyclase via Gi/o proteins, resulting in decreased cAMP production.

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🔬 Protein Info
Gene SymbolHTR1FPROTEIN
Full Name5-Hydroxytryptamine Receptor 1F (5-HT1F)
Protein TypeProtein
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionthe trigeminal ganglion, cortex, hippocampus, and dorsal raphe nucleus, where it modulates neur
UniProt IDSearch UniProt
GeneCardsHTR1FPROTEIN
Human Protein AtlasHTR1FPROTEIN
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING
🔮 Predicted Structure: HTR1FPROTEIN — AlphaFold SEARCH Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

5-Hydroxytryptamine Receptor 1F (5-HT1F)

protein · 711 words

Pathway Diagram

graph TD
    HTR1FPROTEIN["HTR1FPROTEIN"]
    neurodegeneration["neurodegeneration"]
    HTR1FPROTEIN -->|"implicated_in"| neurodegeneration
    style HTR1FPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning HTR1FPROTEIN in their description or question text

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