Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HTR1FPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
The 5-HT1F receptor is a serotonin receptor subtype belonging to the G protein-coupled receptor (GPCR) superfamily. It is negatively coupled to adenylyl cyclase via Gi/o proteins, resulting in decreased cAMP production.
No AI portrait yet
| Gene Symbol | HTR1FPROTEIN |
| Full Name | 5-Hydroxytryptamine Receptor 1F (5-HT1F) |
| Protein Type | Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | the trigeminal ganglion, cortex, hippocampus, and dorsal raphe nucleus, where it modulates neur |
| UniProt ID | Search UniProt |
| GeneCards | HTR1FPROTEIN |
| Human Protein Atlas | HTR1FPROTEIN |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
HTR1FPROTEIN["HTR1FPROTEIN"]
neurodegeneration["neurodegeneration"]
HTR1FPROTEIN -->|"implicated_in"| neurodegeneration
style HTR1FPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning HTR1FPROTEIN in their description or question text
No additional research found