gene

HTR3B

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about HTR3B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

HTR3B Gene

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🧬 Gene Info

Gene Symbol	HTR3B
Full Name	5-Hydroxytryptamine Receptor 3B
Chromosome	11q23.1
Function	HTR3B encodes the 5-HT3B subunit.
Primary Expression	the brain and play roles in cognitive function, attention, and motor control
UniProt ID	[O95274](https://www.uniprot.org/uniprotkb/O95274/entry)
GeneCards	HTR3B
Human Protein Atlas	HTR3B
HTR3A	primary binding partner forming functional 5-HT3 receptors
Serotonin (5-HT)	endogenous ligand
Cholinergic anti-inflammatory pathway	HTR3B-dependent immune modulation
Excitotoxicity	pathological process potentially involving HTR3B
Neuroinflammation	key process modulated by 5-HT
Associated Diseases	Psychiatric disorders
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

HTR3B Gene

gene · 618 words

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Pathway Diagram

graph TD
    HTR3B["HTR3B"]
    neurodegeneration["neurodegeneration"]
    HTR3B -->|"implicated_in"| neurodegeneration
    style HTR3B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning HTR3B in their description or question text

No additional research found