Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about IKBEPSILON: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | IKBEPSILON |
| Protein Family | IκB inhibitor proteins (ankyrin repeat family) |
| Function | IκBε serves as a critical regulator of NF-κB activity with several distinctive functions |
| Primary Expression | Cell-type specific (immune cells, neurons, glia) |
| Subcellular Localization | of both IκBε and bound NF-κB complexes |
| Molecular Weight | 41 kDa |
| Amino Acids | 350 aa |
| UniProt ID | [Q13976](https://www.uniprot.org/uniprot/Q13976) |
| GeneCards | IKBEPSILON |
| Human Protein Atlas | IKBEPSILON |
| Associated Diseases | neurodegeneration |
| Interactions | BRCA1 |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
IKBEPSILON["IKBEPSILON"]
neurodegeneration["neurodegeneration"]
IKBEPSILON -->|"implicated_in"| neurodegeneration
style IKBEPSILON fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||