Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about IKBKA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | IKBKA |
| Full Name | Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Alpha |
| Chromosome | 10q24 |
| Function | IKBKA encodes IKKα, a catalytic subunit of the IκB kinase complex. |
| Primary Expression | most tissues, including brain |
| Pathways | NF-κB, NF-κB Signaling, nfkb |
| UniProt ID | O15111 |
| NCBI Gene ID | 1147 |
| Ensembl ID | ENSG00000115607 |
| OMIM | 600664 |
| GeneCards | IKBKA |
| Human Protein Atlas | IKBKA |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
IKBKA["IKBKA"]
neurodegeneration["neurodegeneration"]
IKBKA -->|"implicated_in"| neurodegeneration
style IKBKA fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning IKBKA in their description or question text
No additional research found