IKBKE

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolIKBKE
Nameinhibitor of nuclear factor kappa B kinase subunit epsilon
Typeprotein-coding
Sourcemygene

Summary

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009].

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