gene

IL17F

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about IL17F: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for IL17F Gene

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🧬 Gene Info

Gene Symbol	IL17F
Full Name	Interleukin-17F
Chromosome	6p12.1
Protein Family	IL-17 family
Function	is a cytokine belonging to the IL-17 family that plays crucial roles in inflammatory responses and autoimmune diseases.
Primary Expression	the central nervous system under inflammatory conditions[@waisman2015]: - Astrocytes: Produce IL-17F in response to inflam
Molecular Weight	~34 kDa (219 amino acids)
Amino Acids	219 aa
Exons	3
Pathways	signaling:** ACT1 (also known as CIKS), TRAF6, MAPK
UniProt ID	Q8WWI1
NCBI Gene ID	112744
Ensembl ID	ENSG00000139324
OMIM	607351
GeneCards	IL17F
Human Protein Atlas	IL17F
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: IL17F — AlphaFold Q8WWI1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

IL17F Gene

gene · 921 words

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Pathway Diagram

graph TD
    IL17F["IL17F"]
    neurodegeneration["neurodegeneration"]
    IL17F -->|"implicated_in"| neurodegeneration
    style IL17F fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found