Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about IL26: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | IL26 |
| Full Name | Interleukin 26 |
| Chromosome | 12q13.12 |
| Protein Family | IL-10 cytokine family |
| Function | is a member of the IL-10 cytokine family that plays important roles in immune modulation and inflammatory responses. |
| Primary Expression | the healthy central nervous system (CNS), emerging evidence suggests that it may be induced under inflammatory conditions |
| Pathways | JAK-STAT signaling, JAK-STAT |
| UniProt ID | Q9NPC3 |
| NCBI Gene ID | 55801 |
| Ensembl ID | ENSG00000136646 |
| OMIM | 605450 |
| GeneCards | IL26 |
| Human Protein Atlas | IL26 |
| IL6 | Pro-inflammatory cytokine amplification |
| CXCL8 (IL-8) | Chemokine for neutrophil recruitment |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
IL26["IL26"]
neurodegeneration["neurodegeneration"]
IL26 -->|"implicated_in"| neurodegeneration
style IL26 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
style neurodegeneration fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning IL26 in their description or question text
No additional research found