CXCL8

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCXCL8
NameC-X-C motif chemokine ligand 8
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is a member of the CXC chemokine family and is a major mediator of the inflammatory response. The encoded protein is commonly referred to as interleukin-8 (IL-8). IL-8 is secreted by mononuclear macrophages, neutrophils, eosinophils, T lymphocytes, epithelial cells, and fibroblasts. It functions as a chemotactic factor by guiding the neutrophils to the site of infection. Bacterial and viral products rapidly induce IL-8 expression. IL-8 also participates with othe

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