Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ITGAX: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ITGAX | data_in | dataset_row | 0.00 |
| h-a5bc82c685 | targeted_by | hypothesis | 1.00 |
| synaptic engulfment | mediates | phenotype | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ITGAX | data_in | dataset_row | 0.00 |
| h-a5bc82c685 | targets | hypothesis | 1.00 |
| 37727065 | highly expressed in | paper | 0.90 |
| TRETINOIN (ATRA) | targets | drug | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Downstream Pathway Selective Modulation: ITGAX (αXβ2) Integr | 0.501 | synaptic-biology | Does SPP1-mediated synaptic engulfment r |
| ITGAX/CD11c Targeting to Eliminate Pro-inflammatory DAM in A | 0.408 | neurodegeneration | Microglial subtypes in neurodegeneration |
Scientific analyses that reference this entity
synaptic biology | 2026-04-07 | 8 hypotheses Top: 0.813
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning ITGAX in their description or question text
No additional research found