Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KCA1B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | KCA1B |
| Chromosome | 5q12 |
| Protein Type | Gene |
| Function | encodes a protein of 191 amino acids that associates with the pore-forming BKα subunit to form the functional BK channel complex. |
| Primary Expression | various tissues including smooth muscle, heart, brain, and endocrine cells |
| Amino Acids | 191 aa |
| Exons | 4 |
| UniProt ID | Q9UQB8 |
| NCBI Gene ID | 6130 |
| GeneCards | KCA1B |
| Human Protein Atlas | KCA1B |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
KCA1B["KCA1B"]
neurodegeneration["neurodegeneration"]
KCA1B -->|"implicated_in"| neurodegeneration
style KCA1B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning KCA1B in their description or question text
No additional research found