gene

KCNA2

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about KCNA2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for KCNA2 Gene

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🧬 Gene Info

Gene Symbol	KCNA2
Full Name	Potassium Voltage-Gated Channel Subfamily A Member 2 (Kv1.2)
Chromosome	1p13.3
Function	KCNA2/Kv1.2 functions as: - Voltage-gated potassium channel: Permits K+ efflux during repolarization - Neuronal excitability regulator: Controls action potential shape and frequency - Axonal conductio
Molecular Weight	71.5 kDa
Amino Acids	499 aa
UniProt ID	P16389
NCBI Gene ID	3737
Ensembl ID	ENSG00000177301
OMIM	176266
GeneCards	KCNA2
Human Protein Atlas	KCNA2
Voltage-gated potassium channel	Permits K+ efflux during repolarization
Neuronal excitability regulator	Controls action potential shape and frequency
Axonal conduction	Important for saltatory conduction in myelinated axons
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KCNA2 — AlphaFold P16389 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

KCNA2 Gene

gene · 1067 words

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KCNA2 Protein

protein · 793 words

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Pathway Diagram

graph TD
    KCNA2["KCNA2"]
    neurodegeneration["neurodegeneration"]
    KCNA2 -->|"implicated_in"| neurodegeneration
    style KCNA2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning KCNA2 in their description or question text

No additional research found