gene

KCNA4

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about KCNA4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

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Summary

Potassium voltage-gated channel gene KCNA4

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🧬 Gene Info

Gene Symbol	KCNA4
Full Name	Potassium Voltage-Gated Channel Subfamily A Member 4
Chromosome	11q14.1
Protein Type	Channel
Function	In the nervous system, Kv1.4 channels play crucial roles in
Molecular Weight	73 kDa
Amino Acids	653 aa
UniProt ID	P22459
NCBI Gene ID	3745
Ensembl ID	ENSG00000113916
OMIM	176267
GeneCards	KCNA4
Human Protein Atlas	KCNA4
Neuronal excitability regulation	Controls action potential repolarization and firing patterns
Neurotransmitter release	Modulates calcium entry through presynaptic voltage-gated calcium channels
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KCNA4 — AlphaFold P22459 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KCNA4 Gene

gene · 630 words

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Pathway Diagram

graph TD
    KCNA4["KCNA4"]
    neurodegeneration["neurodegeneration"]
    KCNA4 -->|"implicated_in"| neurodegeneration
    style KCNA4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KCNA4 in their description or question text

No additional research found