Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KCNAB1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | KCNAB1 |
| Full Name | Potassium Voltage-Gated Channel Subfamily A Member Beta 1 |
| Chromosome | 3p21.31 |
| Protein Family | Kv beta subunit (KCNAB) |
| Protein Type | Channel |
| Function | Kcnab1 plays an important role in the study of neurodegenerative diseases |
| Primary Expression | Brain (hippocampus, cortex), Heart, Pancreas |
| Molecular Weight | 38.7 kDa |
| UniProt ID | Q14721 |
| NCBI Gene ID | 7881 |
| Ensembl ID | ENSG00000144229 |
| OMIM | 604378 |
| GeneCards | KCNAB1 |
| Human Protein Atlas | KCNAB1 |
| N-terminal Domain | Contains the binding site for Kv alpha subunits and determines subunit specificity |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
KCNAB1["KCNAB1"]
neurodegeneration["neurodegeneration"]
KCNAB1 -->|"implicated_in"| neurodegeneration
style KCNAB1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning KCNAB1 in their description or question text
No additional research found