gene

KCND1

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about KCND1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Analyses

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Summary

Page for KCND1 — Potassium Voltage-Gated Channel Subfamily D Member 1

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🧬 Gene Info

Gene Symbol	KCND1
Full Name	Potassium Voltage-Gated Channel Subfamily D Member 1
Chromosome	7p14.3
Protein Type	Channel
Function	encodes a voltage-gated potassium (Kv) channel alpha subunit that forms the ion-conducting pore of the Kv channel complex.
Primary Expression	neurons of the cerebral cortex, hippocampus, and cerebellum
Molecular Weight	56 kDa
Amino Acids	507 aa
UniProt ID	Q8ND76
NCBI Gene ID	3750
Ensembl ID	ENSG00000102128
GeneCards	KCND1
Human Protein Atlas	KCND1
Topology	Six transmembrane domains (S1-S6) with intracellular N- and C-termini
Voltage sensor	S1-S4 segments detect membrane potential changes
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KCND1 — AlphaFold Q8ND76 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

KCND1 — Potassium Voltage-Gated Channel Subfamily D Member 1

gene · 926 words

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KCND1 Protein — Potassium Voltage-Gated Channel Subfamily D Member 1

protein · 973 words

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Pathway Diagram

graph TD
    KCND1["KCND1"]
    neurodegeneration["neurodegeneration"]
    KCND1 -->|"implicated_in"| neurodegeneration
    style KCND1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KCND1 in their description or question text

No additional research found