gene

KCNG4

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about KCNG4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Potassium voltage-gated channel modulator gene KCNG4

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🧬 Gene Info

Gene Symbol	KCNG4
Aliases	Potassium Voltage-Gated Channel Modifier Subunit 4
Chromosome	16q24.1
Function	is a central determinant of neuronal energy demand and calcium entry.
Molecular Weight	52 kDa
UniProt ID	Q9Y698
Ensembl ID	ENSG00000168453
GeneCards	KCNG4
Human Protein Atlas	KCNG4
Network-level targeting	KCNG4 is better viewed as a context-dependent modifier target than a stand-alone lesion gene.[@bocksteins2016][@martens2014]
Biomarker logic	KCNG4 genotype or expression may eventually serve as a stratifier for excitability-dominant endophenotypes.[@lee2020][@reciopoveda2024]
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: KCNG4 — AlphaFold Q9Y698 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

KCNG4 Gene

gene · 723 words

→

KCNG4 Protein (Potassium Voltage-Gated Channel Modifier Subunit 4)

protein · 614 words

→

Pathway Diagram

graph TD
    KCNG4["KCNG4"]
    neurodegeneration["neurodegeneration"]
    KCNG4 -->|"implicated_in"| neurodegeneration
    style KCNG4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning KCNG4 in their description or question text

No additional research found